Golgi Feels DNA’s Pain

نویسندگان

  • Marco Foiani
  • Jiri Bartek
چکیده

The Golgi apparatus consists of disc-like cisternae, stretching around the nucleus through forces exerted by F-actin and the Golgi membrane protein GOLPH3. Farber-Katz et al. now report that DNA damage triggers Golgi dispersal and inhibits vesicular transport through DNA-PK-mediated GOLPH3 phosphorylation, thereby linking the DNA damage response to Golgi regulation.

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عنوان ژورنال:
  • Cell

دوره 156  شماره 

صفحات  -

تاریخ انتشار 2014